N-[3-(tert-Butyldimethylsiloxymethyl)-5-nitrophenyl]acetamide

N-[3-(tert-Butyldimethylsiloxymethyl)-5-nitrophenyl]acetamide

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The title compound, C15H24N2O4Si, was prepared by the reaction of (3-acetamido-5-nitrobenzyl)methanol with tert-butyldimethylsilyl chloride 9021 glow and is a key intermediate in the synthesis of novel nonsymmetrical DNA minor groove-binding agents.There are two independent molecules in the structure, which differ primarily in the copyright tiki mug rotation about the C—O bond next to the Si atom.Two strong N—H.O hydrogen bonds align the molecules into a wide ribbon extending approximately parallel to the b axis.